PARAMETERS OF IMMUNOBIOCHEMICAL MARKERS, C-REACTIVE PROTEIN, INTERLEUKINS (IL-6, IL-1Β) AND TNF-Α IN BLOOD SERUM AND TEAR FLUID IN PATIENTS WITH COMPLICATED CATARACT IN RHEUMATOID ARTHRITIS
Keywords:
C-reactive protein, interleukins (IL-6, IL-1β) and TNF-α, Rheumatoid arthritisAbstract
Relevance: Rheumatoid arthritis (RA) is a chronic inflammatory disease frequently associated with systemic complications, including eye damage.
Materials and Methods: The study involved 60 patients diagnosed with cataracts complicated by rheumatoid arthritis. The control group comprised 30 healthy individuals without signs of cataracts or inflammatory diseases. Blood serum and tear fluid samples were collected from all participants to analyze the concentrations of CRP, IL-6, IL-1β, and TNF-α.
Results: CRP levels were significantly elevated in the blood serum and tear fluid of patients with RA and cataracts compared to the control group (p < 0.01).
References
1. Yusupov, A. A., and G. E. Tulakova. “Phacoemulsification of Complicated Cataract with IOL Implantation in Patients with Rheumatoid Arthritis.” Journal of Healthcare and Life-Science Research 3.6 (2024): 393-399.
2. Yusupov, A. A., and G. E. Tulakova. “Changes in C-reactive Protein, Interleukins (IL-6, IL-1Β) and TNF-A in Blood Serum and Tear Fluid in Patients with Cataract Complicated by Rheumatoid Arthritis.” Journal of Healthcare and Life-Science Research. – 2024. – Т. 3. – №. 6. – С. 326-329.
3. Tulakova, G. E. “Changes in the Activity of Rheumatoid Arthritis in the Postoperative Period of Cataract.” Innovations in Technology and Science Education. – 2024. – Т. 3. – №. 22. – С. 179-190.
4. Tulakova, G. E. “Clinical Manifestations of Rheumatoid Arthritis in the Eye.” Problems of Biology and Medicine. – 2024. – №. 1. – С. 151.
5. Yusupov, A. A., and G. E. Tulakova. “Specificity of Surgical Treatment of Cataract in Patients with Rheumatoid Arthritis.” Advanced Ophthalmology. – 2023. – Т. 1. – №. 1. – С. 183-186.
6. Yusupov, A. A., and G. E. Tulakova. “A Special Approach to Cataract Surgery in Patients with Rheumatoid Arthritis.” Advanced ophthalmology. – 2023. – Т. 1. – №. 1. – С. 183-186.
7. Elmurodovna, T. G. “Specificity of Surgical Treatment of Cataract in Patients with Rheumatoid Arthritis.” Spanish Journal of Innovation and Integrity. – 2022. – Т. 12. – С. 13.
8. Yusupov, A. A., Boboyev, S. A., and G. E. Tulakova. “Specificity of Surgical Treatment of Cataract in Patients with Rheumatoid Arthritis.” Journal of Biomedicine and Practice. – 2022. – Т. 7. – №. 2.
9. Shilovskikh, O. V., and O. V. Safonova. “Surgery of Uveal Cataract. Modern Technologies in Ophthalmology.” Modern Technologies in Ophthalmology (3), 2016. (pp. 206-208).
10. Yugai, M. T., Yugai, M. P., and A. A. Ryabtseva. “The Role of Free Radical Oxidation in the Pathogenesis of Uveal Cataract.” Eroshevskie Readings. 1997. (pp. 380-381).
11. Yadykina, E. V., and E. A. Drozdova. “Modern Approaches to Surgery of Complicated Cataract in Children with Uveitis in Juvenile Idiopathic Arthritis.” Vestnik Orenburgskogo gosudarstvennogo universiteta. № 12. (pp.173-176).
