PREPARATION AND DIAGNOSIS OF SOME HETEROCYCLIC COMPOUNDS OF 2-THIOPYRIMIDINE AND STUDYING THE BIOLOGICAL EFFECTIVENESS OF SOME OF THEM

Abstract

В This work includes the preparation of new derivatives of 2-thiopyrimidine compounds from the reaction of chalcone with thiourea through the basic environment.Chalcone was prepared by reacting equal moles of 1-methyl-2-acetylpyrrole with one of the aromatic benzaldehyde substituents using physical methods and spectroscopic analysis such as melting point, color, 1H-NMR, 13C-NMR, and FT-IR spectroscopy to ensure precision and accuracy. Validity of prepared vehicles. The biological activity was evaluated on two types of bacteria, Escherichia coli and Staphylococcus aureus.