PREPARATION AND DIAGNOSIS OF SOME HETEROCYCLIC COMPOUNDS OF 2-THIOPYRIMIDINE AND STUDYING THE BIOLOGICAL EFFECTIVENESS OF SOME OF THEM

Abstract

New derivatives of 2-thiopyrimidine compounds are prepared in this study by reacting chalcone with thiourea in the basic environment. Equivalent moles of 1-methyl-2-acetylpyrrole and one of the aromatic benzaldehyde substituents were reacted to produce chalcone. To assure accuracy and precision, spectroscopic analytical techniques including melting point, colour, 1H-NMR, 13C-NMR, and FT-IR spectroscopy were employed. Validity of ready automobiles. Staphylococcus aureus and Escherichia coli were the two species of bacteria used to assess the biological activity.