EXTRAHEPATIC MANIFESTATIONS OF CHRONIC VIRAL HEPATITIS C
Keywords:
chronic hepatitis C, extrahepatic manifestations, cryoglobulinemic vasculitis, hemorrhagic vasculitis, liver fibrosisAbstract
The purpose of the study. A retrospective analysis of 319 adult patients aged 18 to 71 years with HCV caused by HCV genotypes 1, 2, 3 who were treated at the Bukhara OIB in the period from 2018 to 2020 was carried out. The main group of patients with fibrotic processes of the F2-F3 stage was 74.1%, and the control group of patients with the F1–F2 stage of fibrotic lesion was 63.8%. Fibrotic lesions of the F0 – F1 stage in the main group amounted to 21.4%, and in the control group 47.9% of cases. Cryoglobulinemic vasculitis was observed in 34.8% of cases, among its manifestations: arthritis 28.2%, hemorrhagic vasculitis 46.2%, peripheral neuropathy 15.4%, chronic glomerulonephritis 5.1%. 2 cases of B-cell lymphoma have been reported in male patients at the stage of liver cirrhosis.
