The Effect of a Fixed Combination of Perindopril and Amlodipine on Intrarenal Hemodynamics and the Functional State of the Kidneys in Patients with Essential Arterial Hypertension

Abstract

In recent years, there has been an increase in the incidence of chronic kidney disease (CKD) and, according to the NHANES III study; the prevalence of kidney dysfunction is 11% [1]. In addition, it has been shown that the presence of CKD is accompanied by an almost 2-fold increase in the prevalence of coronary heart disease, cerebrovascular disease and diabetes mellitus [2, 3].