Can Migraines Cause Latent Depression? From Pathogenesis to Clinic

Abstract

Migraine headache is not rare which often leads to maladjustment of patients of working age, long studied by scientists all over the world and some aspects of the problem to be studied deeper. The defeat of the brain substance, due to vascular changes with migraine, partly leads to the pathology of the psychological status of patients with the development of serious depressive conditions, which further exacerbates and worsens the course of migraine attacks, as well as the intensity and duration of headaches. The clinical data of the study of psychological status according to the Hamilton depression scale are given in the work, depending on the intensity and nature of pain in patients with complicated migraine forms. It is described by groups of manifestations of depression depending on the severity of headaches from one-dimensional pain intensity scales. In the discussion and conclusions, the relationship between headaches and depression in patients with complicated migraine forms is given. In the case of complicated forms of migraine, the frequent occurrence of clinically pronounced depression is associated with focal lesions and abnormalities in the pathological mechanisms of brain activity. The existing depression can aggravate the intensity of the pain syndrome and its duration, leading to a reduction in the periods of remission, developing a continuous chick pain-depression-pain.