BRONCHIAL ASTHMA AND CARDIOVASCULAR COMPLICATIONS

Authors

  • Ergasheva Ma’mura Toshtemirovna Assistant at the Department of Propaedeutics of Internal Diseases, Samarkand State Medical University. Uzbekistan
  • Kamalova Diyora Jamshedovna Assistant at the Department of Propaedeutics of Internal Diseases, SamSMU. Uzbekistan
  • Bekmuradova Makhsuda Salkhidinovna PhD, Assistant at the Department of Propaedeutics of Internal Diseases. SamSMU. Uzbekistan

Keywords:

Bronchial Asthma, Cardiovascular Complications, Inflammation, C-Reactive Protein, Interleukin-6, Blood Pressure, Heart Rate, Systemic Inflammation

Abstract

This study investigates the association between bronchial asthma and cardiovascular diseases, addressing a significant knowledge gap regarding the impact of chronic respiratory conditions on cardiovascular health. Despite existing evidence suggesting a link, comprehensive data specifically examining inflammatory markers in asthmatic patients remain limited. We conducted a cross-sectional analysis involving 500 participants, including 250 individuals diagnosed with asthma and 250 control subjects. Key cardiovascular health markers, such as blood pressure, heart rate, and inflammatory cytokines (C-Reactive Protein and Interleukin-6), were assessed. The findings revealed that asthmatic patients exhibited significantly higher blood pressure (p < 0.001), elevated heart rates (p < 0.01), and increased levels of CRP and IL-6 (p < 0.001) compared to controls. These results suggest a concerning trend of cardiovascular risk factors in patients with bronchial asthma. The implications of this study highlight the necessity for integrated healthcare approaches that include routine cardiovascular assessments for asthmatic patients to mitigate potential risks. Future research should focus on longitudinal studies to elucidate the causal relationship between asthma and cardiovascular diseases, as well as the effects of various asthma treatments on cardiovascular outcomes.

References

1. Alisherovna, K. M., & Djamshedovna, K. D. (2024). AFTER COVID-19 QUALITY OF LIFE. Spectrum Journal of Innovation, Reforms and Development, 25, 103-110.

2. Alisherovna, K. M., Djamshedovna, K. D., Totlibayevich, Y. S., & Boymamatovna, E. F. (2022). The Effectiveness of the Original Drug Trimetazidine MV in Patients with Stable Ischemic Heart Disease and Persistent Angina Attacks Against the Background of the Use of Trimetazidine Generics. Miasto Przyszłości, 30, 235-238.

3. Alisherovna, K. M., Erkinovna, K. Z., Djamshedovna, K. D., & Nizamitdinovich, K. S. (2023). QUALITY OF LIFE PATIENTS WITH OSTEOARTHRITIS. Journal of new century innovations, 36(1), 164-175.

4. Alisherovna, K. M., Erkinovna, K. Z., Jamshedovna, K. D., & Toshtemirovna, E. M. M. (2022). Study of qualityof life indicators in patients with coronary heart disease using the sf-36 questionnaire.

5. Alisherovna, K. M., Tatlibayevich, Y. S., Toshtemirovna, E. M. M., & Nizamitdinovich, H. S. (2021). Diagnostic Significance Daily Monitoring of Blood Pressure in Young Women (Under 40 Years Old) with Arterial Hypertension. Central Asian Journal of Medical and Natural Science, 2(5), 461-465.

6. Alisherovna, K. M., Toshtemirovna, E. M. M., Djamshedovna, K. D., & Maxammadiyevich, K. S. (2022). Endothelial Dysfunction in Patients with Chronic Heart Failure. Miasto Przyszłości, 30, 218-220.

7. Alisherovna, K. M., Toshtemirovna, E. M. M., Duskobilovich, B. S., & Umirxanovna, K. G. (2022). DYSFUNCTION LEFT VENTRICULAR IN BRONCHIAL ASTHMA. Spectrum Journal of Innovation, Reforms and Development, 4, 216-221.

8. Alisherovna, Khusainova Munira, Sultonov Ilkhom Islomovich, and Kamolova Diyora Djamshedovna. "PSYCHOEMOTIONAL STATE AND QUALITY OF LIFE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS." Ta'lim innovatsiyasi va integratsiyasi 31.2 (2024): 124-131.

9. Cepelis A, Brumpton BM, Laugsand LE, Dalen H, Langhammer A, Janszky I, et al. Asthma, asthma control and risk of acute myocardial infarction: HUNT study. Eur J Epidemiol. 2019;34:967–77.

10. Djamshedovna, Kamolova Diyora, and Khusainova Munira Alisherovna. "CHANGES IN SOME SYSTEM INDICATORS IN PREGNANT WOMEN WITH GESTOSIS." Spectrum Journal of Innovation, Reforms and Development 25 (2024): 111-115.

11. Djamshedovna, Kamolova Diyora, Khusainova Munira Alisherovna, and Sultonov Ilkhom Islomovich. "ARTERIAL HYPERTENSION IN RHEUMATOID ARTHRITIS." Ta'lim innovatsiyasi va integratsiyasi 31.2 (2024): 139-145.

12. Djamshedovna, Kamolova Diyora. "Echocardiographic signs F chf in patients with essential hypertension." (2021).

13. Djamshedovna, Kamolova Diyora. "Echocardiographic signs F chf in patients with essential hypertension." (2021).

14. Djamshedovna, Kamolova Diyora. "TREATMENT OF ARTERIAL HYPERTENSION IN PREGNANT WOMEN." Ta'lim innovatsiyasi va integratsiyasi 31.2 (2024): 146-154.

15. Dong JY, Zhang YH, Qin LQ. Obstructive sleep apnea and cardiovascular risk: meta-analysis of prospective cohort studies. Atherosclerosis. 2013;229:489–95.

16. Erkinovna, K. Z., Alisherovna, K. M., Bakhtiyorovich, U. J., & Djamshedovna, K. D. (2023). METABOLIC SYNDROME IN RHEUMATOID ARTHRITIS. Journal of new century innovations, 38(2), 203-211.

17. Fang ZH, Li ZF, An ZY, Huang SC, Hao MD, Zhang WX. Meta-analysis of the association between asthma and the risk of stroke. Front Neurol. 2022;13:900438.

18. Hua ML, Li L, Diao LL. Bronchial asthma and risk of 4 specific cardiovascular diseases and cardiovascular mortality: a meta-analysis of cohort studies. Eur Rev Med Pharm Sci. 2022;26:5081–91.

19. Hultén LM, Levin M. The role of hypoxia in atherosclerosis. Curr Opin Lipidol. 2009;20:409–14.

20. Islomovich, Sultonov Ilkhom, Khusainova Munira Alisherovna, and Kamolova Diyora Djamshedovna. "FACTORS OF OSTEOPOROSIS IN PATIENTS WITH CORONARY HEART DISEASE IN COMBINATION WITH RHEUMATOID ARTHRITIS." Ta'lim innovatsiyasi va integratsiyasi 31.2 (2024): 132-138.

21. Jamshedovna, Kamolova Diyora, and Ergasheva Ma’mura Tashtemirovna. "HOMILADOR AYOLLARDA ARTERIAL GIPERTENZIYA VA CHAP QORINCHA DIASTOLIK DISFUNKTSIYASI XUSUSIYATLARI BAXOLASH." Journal of new century innovations 53.3 (2024): 25-28.

22. Khabibovna, Y. S., Alisherovna, K. M., Erkinovna, K. Z., & Djamshedovna, K. D. (2023). Gender Characteristics of the Course of Rheumatoid Arthritis. Miasto Przyszłości, 40, 438-442.

23. Khabibovna, Y. S., Zhamshedovna, K. D., Davranovna, M. K., & Yusuphovich, N. F. (2022). FUNCTIONAL STATE OF THE MYOCARDIA IN DEVELOPMENTAL PATHOGENESIS CHRONIC HEART FAILURE IN PATIENTS WITH HYPERTENSION. Novateur Publications, 1-72.

24. Khusainova, M. A., Bekmuradova, M. S., Makhmudova, K. D., & Uzokov, J. B. (2023). Echocardiographic changes of the left ventricle in bronchial asthma. Science and Education, 4(5), 214-221.

25. Khusainova, M. A., Toirov, D. R., Khaydarov, S. N., & Kamolova, D. D. (2023). MORPHOFUNCTIONAL PARAMETERS OF THE HEART IN WOMEN SUFFERING FROM ESSENTIAL ARTERIAL HYPERTENSION IN POSTMENOPAUSE AND ON THE BACKGROUND OF TREATMENT. Oriental renaissance: Innovative, educational, natural and social sciences, 3(1), 322-330.

26. Lee CJ, Hwang J, Kang CY, Kang D, Kim DH, Park HJ, et al. Asthma and increased risk of myocardial infarction and mortality among hypertensive Korean patients. Hypertens Res. 2023. https://doi.org/10.1038/s41440-023-01257-3.

27. Müllerová H, Marshall J, de Nigris E, Varghese P, Pooley N, Embleton N, et al. Association of COPD exacerbations and acute cardiovascular events: a systematic review and meta-analysis. Ther Adv Respir Dis. 2022;16:17534666221113647.

28. Nazarov F. Y. et al. Cardiovascular Changes in Patients During the Post-Covid //Miasto Przyszłości. – 2024. – Т. 51. – С. 528-532.

29. Nazarov F. Y. et al. Post-Covid Pneumonia Sequelae //American Journal of Biology and Natural Sciences. – 2024. – Т. 1. – №. 6. – С. 1-6.

30. Pujades-Rodriguez M, Morgan AW, Cubbon RM, Wu J. Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: a population-based cohort study. PLoS Med. 2020;17:e1003432.

31. Rustamovich, T. D., Alisherovna, K. M., Djamshedovna, K. D., & Nizamitdinovich, K. S. (2023). Features of the psychoemotional status of patients with rheumatoid arthritis. Miasto Przyszłości, 32, 23-30.

32. Rustamovich, T. D., Alisherovna, K. M., Nizamitdinovich, K. S., & Djamshedovna, K. D. (2022). Gastrointestinal conditions in rheumatoid arthritis patients. Texas Journal of Medical Science, 15, 68-72.

33. Rustamovich, Toirov Doston. "YURAK ISHEMIK KASALLIGI SABABLARI." ENG YAXSHI XIZMATLARI UCHUN 1.6 (2023): 571-573.

34. Salkhidinovna B. M. et al. Assessment of the Psychological State in Patients With Ischemic Heart Disease //Research Journal of Trauma and Disability Studies. – 2024. – Т. 3. – №. 9. – С. 147-153.

35. Salkhidinovna B. M. et al. Psychological Impacts and Treatment Strategies in Patients With Liver Cirrhosis //Research Journal of Trauma and Disability Studies. – 2024. – Т. 3. – №. 9. – С. 140-146.

36. Salkhidinovna B. M. et al. THE IMPORTANCE OF REHABILITATION AND CARE FOR PATIENTS WHO HAVE SUFFERED A MYOCARDIAL INFARCTION //EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE. – 2024. – Т. 4. – №. 9. – С. 387-392.

37. Tashtemirovna, Ergasheva Ma’mura, et al. "Angiopathy in Rheumatoid Arthritis." Miasto Przyszłości 40 (2023): 418-425.

38. Tashtemirovna, Ergasheva Ma’mura, et al. "Angiopathy in Rheumatoid Arthritis." Miasto Przyszłości 40 (2023): 418-425.

39. Tatlibayevich, Yarmatov Suvon, and Normatov Murodjon Buribayevich. "FEATURES OF THE QUALITY OF LIFE IN PATIENTS WITH PNEUMONIA." World Bulletin of Public Health 27 (2023): 53-57.

40. Tatlibayevich, Yarmatov Suvon. "FACTORS OF INFLAMMATION IN PATIENTS WITH ARTERIAL HYPERTENSION AND DIABETES MELLITUS." Spectrum Journal of Innovation, Reforms and Development 24 (2024): 46-53.

41. Toshtemirovna, E. M. M., Alisherovna, K. M., Erkinovna, K. Z., & Xudoyberdiyevich, G. X. (2022). DIAGNOSIS OF CIRRHOTIC CARDIOMYOPATHY. Spectrum Journal of Innovation, Reforms and Development, 10, 141-147.

42. Toshtemirovna, Ergasheva Ma’mura, et al. "THE VALUE OF XANTHINE IN CHRONIC HEART FAILURE." Spectrum Journal of Innovation, Reforms and Development 4 (2022): 24-29.

43. Toshtemirovna, Ergashova Ma’mura, et al. "Anxiety Disorders and Coronary Heart Disease." The Peerian Journal 11 (2022): 58-63.

44. Wang MT, Liou JT, Lin CW, Tsai CL, Wang YH, Hsu YJ, et al. Association of cardiovascular risk with inhaled long-acting bronchodilators in patients with chronic obstructive pulmonary disease: a nested case-control study. JAMA Intern Med. 2018;178:229–38.

45. Wang X, Ouyang Y, Wang Z, Zhao G, Liu L, Bi Y. Obstructive sleep apnea and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies. Int J Cardiol. 2013;169:207–14.

46. Xudoyberdiyevich, G. X., Alisherovna, K. M., Toshtemirovna, E. M. M., & Totlibayevich, Y. S. (2022). Characteristics Of Neuropeptides-Cytokines in Patients with Cardiovascular Pathology Occurring Against the Background of Anxiety and Depressive Disorders. The Peerian Journal, 11, 51-57.

47. Yarmatov, Suvon Totliboyevich, and Munira Alisherovna Xusainova. "BRONXIAL ASTMA MAVJUD BO’LGAN BEMORLARDA GASTROEZOFAGIAL REFLYUKS KASALLIGI DIAGNOSTIKASI VA OLIB BORISH ALGORITMI." Scientific progress 2.2 (2021): 208-213.

48. Yarmatov, Suvon Totliboyevich. "Yurak Ishemik Kasalligi Va Bachadon Miomasi Bo'lgan Bemorlarni Davolashda Antikougulyant Va Antitrombositar Terapiyani O’tkazish Bo’yicha Klinik Kuzatuvni Olib Borish." Scientific progress 2.3 (2021): 792-797.

49. Yarmukhamedova, S., Nazarov, F., Mahmudova, X., Vafoeva, N., Bekmuradova, M., Gaffarov, X., ... & Xusainova, M. (2020). Features of diastolic dysfunction of the right ventricle in patients with hypertonic disease. Journal of Advanced Medical and Dental Sciences Research, 8(9), 74-77.

50. Zhang B, Li ZF, An ZY, Zhang L, Wang JY, Hao MD, et al. Association between asthma and all-cause mortality and cardiovascular disease morbidity and mortality: a meta-analysis of cohort studies. Front Cardiovasc Med. 2022;9:861798.

51. Бекмурадова М. С., Назаров Ф. Ю. ТАКТИКА ПРИМЕНЕНИЯ ИНГИБИТОРОВ ПРОТОННОЙ ПОМПЫ С ПЕЧЕНОЧНОЙ ЭНЦЕФАЛОПАТИИ У БОЛЬНЫХ ЦИРРОЗОМ ПЕЧЕНИ //Вестник магистратуры. – 2022. – №. 2-1 (125). – С. 7-9.

52. Бекмурадова, Махсуда Салхидиновна, and Санжар Низомиддинович Хайдаров. "Связь между повышенным пульсовым давлением и натрийуретическим пептидом." Journal of cardiorespiratory research 3.1 (2022): 26-29.

53. Камолова, Диёра Жамшедовна, and Мамура Таштемировна Эргашева. "Особенности ремоделирования сердца и сосудов у беременных при артериальной гипертензии." Science and Education 4.5 (2023): 581-588.

54. Назаров Ф. Ю., Ярмухамедова С. Х., Бекмурадова М. С. Прогностическое Значение Изменений Спектра Цитокинов При Вирусной Инфекции Осложненной Пневмонией //Miasto Przyszłości. – 2024. – Т. 46. – С. 990-996.

55. Назаров Ф. Ю., Ярмухамедова С. Х., Бекмурадова М. С. Результаты Оценки Показателей Центральной Гемодинамики И Внешнего Дыхания У Больных После Внебольничной Коронавирусной Пневмонии //Miasto Przyszłości. – 2024. – Т. 46. – С. 981-989.

56. Ярмухамедова С. Х., Бекмурадова М. С., Назаров Ф. Ю. Значение уровня мозгового натрийуретического пептида в ранней диагностике хронической сердечной недостаточности у больных с артериальной гипертонией //Достижения науки и образования. – 2020. – №. 4 (58). – С. 61-63.

Downloads

Published

2024-10-30

How to Cite

Toshtemirovna, E. M., Jamshedovna, K. D., & Salkhidinovna, B. M. (2024). BRONCHIAL ASTHMA AND CARDIOVASCULAR COMPLICATIONS. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(10), 436–443. Retrieved from http://inovatus.es/index.php/ejmmp/article/view/4323

Similar Articles

<< < 24 25 26 27 28 29 30 31 32 33 > >> 

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)