BIOLOGICAL AND PHYSIOLOGICAL EFFECTS OF AFLATOXIN ON MICE LIVER FUNCTION ENZYMES

Authors

  • Mayssam Ali Hamada Hassan Al-Nahrain University College of Biotechnology Department of molecular and medical biotechnology
  • Ahmed Abd al-Hussain Abd al-Sadah Atban Al-Qasim Green University College biotechnology Department biotechnology
  • Assel Ammer Ali Mohammed University of Fallujah College of applied science Department of Biotechnology
  • Amir Abd al-Hussain Abd al-Sadah Atban Al-Qasim Green University College biotechnology Department biotechnology

Abstract

In this study, the biological and physiological effect of aflatoxin was evaluated by detecting the mouse serum level of liver functional enzymes (AST, ALT and ALP). Three groups of animals (mice) were taken. First and second groups treated with aflatoxin at concentrations 0.75 and 1.5 ppm respectively for 14 successive days, while the third group treated with distilled water as negative control. Results indicated that the aflatoxin caused a significant dose dependent, increase in serum liver functional enzymes levels with maximum level following 1.5 ppm administration 236.00, 162.44, 97.56 U/L for AST, ALT and ALP, respectively.

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Published

2024-08-24

How to Cite

Mayssam Ali Hamada Hassan, Ahmed Abd al-Hussain Abd al-Sadah Atban, Assel Ammer Ali Mohammed, & Amir Abd al-Hussain Abd al-Sadah Atban. (2024). BIOLOGICAL AND PHYSIOLOGICAL EFFECTS OF AFLATOXIN ON MICE LIVER FUNCTION ENZYMES. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(8), 528–536. Retrieved from https://inovatus.es/index.php/ejmmp/article/view/3885

Issue

Vol. 4 No. 8 (2024): European Journal of Modern Medicine and Practice

Section

Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.