SYNTHESIS AND CHARACTERIZATION OF TETRA 1,2,4,5 SUBSTITUTED IMIDAZOLE’S

Authors

  • Zainab Mohammed To’ma Ahmed University of kerbala College of science, Department of chemistry
  • Safa Muhammad Mahmoud Jadoua University of Kufa College of science, Department of chemistry
  • Reem Hassan Mohammed Ali Bashboush University of Kufa College of science, Department of chemistry
  • Sabreen Turki Attia Rashid University of Anbar, College of Science, Department of Chemistry
  • Doaa Najem Abed Jweid University of baghdad /College of science / Department chemistry

Abstract

In this work new series of 1,2,4,5 tetrasubstituted imidazole 5a-d derivatives have been synthesized via four-component, one-pot reaction of 1,2-diketones, substituted aryl aldehydes, ammonium acetate and aromatic amine in good yields by Radiszewski Synthesis in presence of glacial acetic acid as a catalyst under reflux condition. The characterizations of all synthesized compounds were mostly carried out by thin layer chromatography (TLC), melting point and Fourier-transform infrared spectroscopy (FT-IR).

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Published

2024-08-10

How to Cite

Zainab Mohammed To’ma Ahmed, Safa Muhammad Mahmoud Jadoua, Reem Hassan Mohammed Ali Bashboush, Sabreen Turki Attia Rashid, & Doaa Najem Abed Jweid. (2024). SYNTHESIS AND CHARACTERIZATION OF TETRA 1,2,4,5 SUBSTITUTED IMIDAZOLE’S. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(8), 85–99. Retrieved from https://inovatus.es/index.php/ejmmp/article/view/3800

Issue

Vol. 4 No. 8 (2024): European Journal of Modern Medicine and Practice

Section

Articles