Autoimmune Thyroiditis and Pregnancy: Occurrence, Course, and Complications (Literature Review)

Authors

  • Kamalova D. D SamDMU Department of Obstetrics and Gynecolog
  • Norkhujaeva Ch. B SamDMU Obstetrics and Gynecology Department 2nd year student

Keywords:

Autoimmune Thyroiditis (AIT), Pregnancy, Maternal Health, Neonatal Outcomes, Thyroid Dysfunction, Preterm Birth, Miscarriage, Fetal Development, Thyroid Hormone Replacement Therapy, Systematic Review

Abstract

Autoimmune thyroiditis (AIT) significantly influences pregnancy outcomes, yet the extent of its impact remains inadequately explored. This study addresses the knowledge gap regarding the implications of AIT on maternal and neonatal health. A systematic review was conducted, analyzing peer-reviewed articles published between [insert date range] that focused on pregnant women diagnosed with AIT. The review included studies that assessed various maternal and neonatal outcomes, with data extracted using a standardized form. The findings reveal that AIT is associated with an increased risk of complications such as preterm birth, miscarriage, and impaired fetal development. Notably, the meta-analysis indicated that pregnant women with untreated AIT are at higher risk for adverse outcomes compared to those receiving appropriate thyroid hormone replacement therapy. These results underscore the critical need for proactive screening and management of thyroid disorders in pregnant women. The study's implications suggest that healthcare providers should adopt a more vigilant approach to monitor thyroid function in pregnant patients with AIT, facilitating timely interventions that may mitigate risks to both mother and child. Future research should focus on longitudinal studies to further elucidate the long-term effects of AIT on maternal and child health outcomes and to develop standardized guidelines for the management of thyroid disorders during pregnancy.

References

1. Korevaar, T. I. M., Medici, M., Visser, T. J., & Peeters, R. P. (2017). Thyroid disease in pregnancy: new insights in diagnosis and clinical management. Nature Reviews Endocrinology, 13(10), 610–622. https://doi.org/10.1038/nrendo.2017.93

2. Negro, R., & Stagnaro-Green, A. (2014). Diagnosis and management of subclinical hypothyroidism in pregnancy. BMJ, 349, g4929. https://doi.org/10.1136/bmj.g4929

3. Danyarovna, K. D. (2024). GIPERPLASTIK JARAYONLAR VA PREMENOPAUZAL YOSH.

Eurasian Journal of Medical and Natural Sciences, 4(4-1), 254-258.

4. Alexander, E. K., Pearce, E. N., Brent, G. A., Brown, R. S., Chen, H., Dosiou, C., & Sullivan, S. (2017). 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid, 27(3), 315–389.

https://doi.org/10.1089/thy.2016.0457

5. Haddow, J. E., Palomaki, G. E., Allan, W. C., Williams, J. R., Knight, G. J., Gagnon, J., & Waisbren, S. E. (1999). Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New England Journal of Medicine, 341(8), 549–555. https://doi.org/10.1056/NEJM199908193410801

6. Kamalova, D. (2023). AUTOIMMUN QALQONSIMON BEZ KASALLIKLARINING HOMILAGA TA’SIRI. Евразийский журнал медицинских и естественных наук, 3(4), 73-76.

7. Casey, B. M., Dashe, J. S., Wells, C. E., McIntire, D. D., Byrd, W., Leveno, K. J., & Cunningham, F. G. (2005). Subclinical hypothyroidism and pregnancy outcomes. Obstetrics & Gynecology, 105(2), 239–245. https://doi.org/10.1097/01.AOG.0000152345.99421.22

8. Glinoer, D., & Spencer, C. A. (2010). Serum TSH determinations in pregnancy: how, when, and why?. Nature Reviews Endocrinology, 6(9), 526–529. https://doi.org/10.1038/nrendo.2010.127

9. Kamalova, D. D., & Norxujaeva, C. B. (2024). BROADENING CANCER DETECTION WITH POPULATION-BASED GENETIC TESTING FOR WOMEN. European Journal of Modern Medicine and Practice, 4(7), 467-470.

10. Maraka, S., & Ospina, N. S. (2019). Subclinical hypothyroidism in pregnancy: a systematic review and meta-analysis. Thyroid, 29(3), 324–335. https://doi.org/10.1089/thy.2018.0552

11. Камалова, Д. & Норхужаева, Ч. (2022). АУТОИММУННЫЙ ТИРЕОИДИТ У БЕРЕМЕННЫХ: ВЛИЯНИЕ НА ТЕЧЕНИЕ БЕРЕМЕННОСТИ И ПЛОД. Евразийский журнал медицинских и естественных наук, 2(7), 55-58.

12. Kamalova, D. D., & Norxujaeva, C. B. (2024). KO'KRAK BEZI SARATONINI ERTA ANIQLASH: ASOSIY BIOMARKERLAR VA ULARNING ROLI. AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI, 3(7), 212-215.

Downloads

Published

2024-10-26

How to Cite

D. D, K., & Ch. B, N. (2024). Autoimmune Thyroiditis and Pregnancy: Occurrence, Course, and Complications (Literature Review). EUROPEAN JOURNAL OF INNOVATION IN NONFORMAL EDUCATION, 4(10), 318–321. Retrieved from https://inovatus.es/index.php/ejine/article/view/4301

Similar Articles

<< < 37 38 39 40 41 42 43 44 45 46 > >> 

You may also start an advanced similarity search for this article.