MUCOADHESIVE DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW

Authors

  • Ishita Biswas Student, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India
  • Mrs. Chetana Tripathi Assistant Professor, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India
  • Dr. Himani Tiwari HOD, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India
  • Dr. Kaushal K Chandrul Dean, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India

Keywords:

Mucoadhesion, theories, mucoadhesive dosage forms

Abstract

Mucoadhesive drug delivery systems stick to the mucus layer that covers the mucosal epithelial surface. This interaction with mucus and mucin molecules helps the drug stay longer at the absorption site. Drugs that act locally or are best absorbed in the gastrointestinal tract (GIT) benefit from staying longer in the GIT, as it boosts drug levels in the blood and improves their effectiveness. This review explains how mucoadhesion works, the factors that affect mucoadhesive devices, and the different types of mucoadhesive dosage forms.

Author Biographies

Dr. Himani Tiwari, HOD, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India

Mucoadhesive drug delivery systems stick to the mucus layer that covers the mucosal epithelial surface. This interaction with mucus and mucin molecules helps the drug stay longer at the absorption site. Drugs that act locally or are best absorbed in the gastrointestinal tract (GIT) benefit from staying longer in the GIT, as it boosts drug levels in the blood and improves their effectiveness. This review explains how mucoadhesion works, the factors that affect mucoadhesive devices, and the different types of mucoadhesive dosage forms.

Dr. Kaushal K Chandrul, Dean, Department of Pharmacy, Faculty of Pharmaceutical Science, Mewar University, Chittorgarh, Rajasthan, India

Mucoadhesive drug delivery systems stick to the mucus layer that covers the mucosal epithelial surface. This interaction with mucus and mucin molecules helps the drug stay longer at the absorption site. Drugs that act locally or are best absorbed in the gastrointestinal tract (GIT) benefit from staying longer in the GIT, as it boosts drug levels in the blood and improves their effectiveness. This review explains how mucoadhesion works, the factors that affect mucoadhesive devices, and the different types of mucoadhesive dosage forms.

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Published

2024-05-30

How to Cite

Biswas, I. ., Tripathi, M. C. ., Tiwari, D. H. ., & Chandrul, D. K. K. . (2024). MUCOADHESIVE DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(5), 366–374. Retrieved from http://inovatus.es/index.php/ejmmp/article/view/3311

Issue

Vol. 4 No. 5 (2024): European Journal of Modern Medicine and Practice

Section

Articles

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