FEATURES OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH TYPE II DIABETES MELLITUS

Abstract

Type 2 diabetes (T2DM) is one of the most common non-communicable diseases worldwide. According to WHO data from 2016, the number of people with diabetes has increased to 422 million [1]. According to WHO forecasts, diabetes will be the 7th leading cause of death in 2030 [2]. It is known that diabetes is dangerous due to its severe complications, which lead to disability of patients, deterioration in the quality of life and premature mortality. Chronic hyperglycemia is a leading factor in the development of vascular complications of diabetes with damage to various organs, especially the organs of vision, kidneys, cardiovascular and nervous systems. Early and effective prevention of these conditions requires optimal treatment from the moment the disease is identified, achieving and maintaining target metabolic parameters throughout the patient's life. Chronic kidney disease (CKD) is a supranosological concept that generalizes kidney damage or a decrease in glomerular filtration rate (GFR) <60 ml/min/1.73 m2, persistent for more than 3 months, regardless of the primary diagnosis [3]. The growing population of patients with diabetes and CKD is one of the most serious problems in modern medicine.